general interests: synthetic biology, bacteria, living matter, procedural art, interactive music\sculpture
Education:
2006-present
Rockefeller University (link)
PhD candidate, genetically encoded small molecules\biophysics
1999-2003
Princeton University (link)
BA molecular biology (music performance cert.)
Experience:
2003-2006
Research Assistant (link)
Rockefeller University, Laboratory of Chemistry and Cell Biology Dr. Tarun M. Kapoor
Single molecule biophysical characterizations of mitotic kinesins (eg5, kif2a, etc.)
High throughput phenotypic screening of kinase inhibitor scaffolds
in silico screening of small molecule libraries
2003-2006
DJ\Composer\Freelance musician\instructor
Arshiles, Liquids, NYU, 826NYC, MoMA, LIC Space, Rockefeller University, Princeton Art Museum, BB Kings w Maxi Priest
2002-2003
Technology Consultant\Intern
MoMA Warmup Summer Music Series (P.S.1)
2001-2003
Undergraduate Research Fellow
Princeton University, Laboratory of George McLendon (link)
in silico screening of tetrapeptide mimics to inhibit the SMAC-diablo interaction. (caspase-apoptosis pway)
2001-2003
Co-founder of design firm, chief designer: Design HCA
Clients: Rem Koolhaas, appliedradiology, flux art space, princeton university,
2000-1999
Volunteer\Summer Intern
Marine Biology Laboratory, Laboratory of Mitchell Sogin
PERL programming and scripting to parse genomic data from the Giardia Genome Project.
1998-2000
Freelance Graphic Designer\ Web Designer
Applied Radiology.com
Publications:
"The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks" Kapitein LC, Peterman EJ, Kwok BH, Kim JH, Kapoor TM, Schmidt CF. Nature May 2005. Pubmed
"Allosteric inhibition of kinesin-5 modulates its processive directional motility" Kwok BH, Kapitein LC, Kim JH, Peterman EJ, Schmidt CF, Kapoor TM. Nature Chemical Biology September 2006. Pubmed
"Probing cell-division phenotype space and Polo-like kinase function using small molecules" Ulf Peters, Joseph Cherian, Jeffrey H Kim, Benjamin H Kwok and Tarun M Kapoor Nature Chemical Biology October 2006. Pubmed
"Unlocking Environmental DNA Derived Gene Clusters Using a Metagenomics Approach" Kim, JH. Simmons TL, Brady, SF Comprehensive Natural Products Chemistry (CONAP part deux!) 2009. Amazon
"Expanding small molecule functional metagenomics through parallel screening of broad host-range cosmid environmental DNA libraries in diverse proteobacteria" Craig JC, Yuan-Chang FC, Kim JF, Obiajulu SC, Brady SF. Applied and Environmental Microbiology 2009 Pubmed
"Metagenomic Approaches to Natural Products from Free-Living and Symbiotic Organisms" Brady SF, Simmons TL, Kim JH, Schmidt EW. Natural Products Reports 2009 Pubmed
Please email me to request a PDF version of the CV (email)
Expertise:
Programming: Matlab, R, LabView, C++, Perl, PHP, MySql, Python
Research: Single molecule imgaing, confocal microscopy, cell culture, high throughput assay design, advanced image segmentation and analysis, metagenomic library construction and screening techniques, high molecular weight DNA assembly systems.
Training: 454 sequencing training, GE FPLC, LC/MS, Perkin Elmer automation training
Machining, basic welding, basic woodworking, electronics and circuit design
Art: Max/MSP, Live, ProTools, Digital Performer, Processing, Arduino